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Take this medication once daily as prescribed with a full glass of water with or without food. Premarin may be administered for a cyclic treatment which consists of 25 days on followed by 5 days. Do not take in larger amounts than prescribed. Individual dosage depends on your condition (for hypogonadism 0.3 mg or 0.625 mg daily, for preventing postmenopausal osteoporosis is 0.3 mg/day). Try your best to take it regularly to get the best benefit from it. Do not take with grapefruit juice, it increases levels of estrogen.
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Long-term treatment with Premarin may increase risk of breast cancer, endometrial hyperplasia, heart attack, or stroke so monitoring of the patient's state should be done on a regular basis. This medication can be harmful to an unborn baby, do not use it during pregnancy. Do not use Premarin to prevent hart disease or dementia. To avoid endometrial hyperplasia you may be prescribed to take a progestin together with Premarin. Do not use this drug if you are under 18 y.o..
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